Detalles de la búsqueda
1.
Cefepime-Taniborbactam in Complicated Urinary Tract Infection.
N Engl J Med
; 390(7): 611-622, 2024 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38354140
2.
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection.
N Engl J Med
; 386(14): 1327-1338, 2022 04 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35388666
3.
Food and Drug Administration Public Workshop Summary-Development Considerations of Antifungal Drugs to Address Unmet Medical Need.
Clin Infect Dis
; 77(3): 380-387, 2023 08 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37021650
4.
An open randomized multicentre Phase 2 trial to assess the safety of DAV132 and its efficacy to protect gut microbiota diversity in hospitalized patients treated with fluoroquinolones.
J Antimicrob Chemother
; 77(4): 1155-1165, 2022 03 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-35016205
5.
First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of SPR720, a Novel Oral Bacterial DNA Gyrase (GyrB) Inhibitor for Mycobacterial Infections.
Antimicrob Agents Chemother
; 65(11): e0120821, 2021 10 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34491803
6.
Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum-ß-Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia Caused by ESBL-Producing Klebsiella pneumoniae.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32253209
7.
Evidence-Based Study Design for Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia.
J Infect Dis
; 219(10): 1536-1544, 2019 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30649434
8.
Fosfomycin for Injection (ZTI-01) Versus Piperacillin-tazobactam for the Treatment of Complicated Urinary Tract Infection Including Acute Pyelonephritis: ZEUS, A Phase 2/3 Randomized Trial.
Clin Infect Dis
; 69(12): 2045-2056, 2019 11 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-30861061
9.
Safety, Pharmacokinetics, and Food Effect of Tebipenem Pivoxil Hydrobromide after Single and Multiple Ascending Oral Doses in Healthy Adult Subjects.
Antimicrob Agents Chemother
; 63(9)2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31262768
10.
Pharmacodynamics of Tebipenem: New Options for Oral Treatment of Multidrug-Resistant Gram-Negative Infections.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31109982
11.
Software for Dosage Individualization of Voriconazole: a Prospective Clinical Study.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30670416
12.
Subgroup analysis and interpretation for phase 3 confirmatory trials: White paper of the EFSPI/PSI working group on subgroup analysis.
Pharm Stat
; 18(2): 126-139, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30592133
13.
Optimizing the Design and Analysis of Clinical Trials for Antibacterials Against Multidrug-resistant Organisms: A White Paper From COMBACTE's STAT-Net.
Clin Infect Dis
; 67(12): 1922-1931, 2018 11 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-30107400
14.
Progress in the Fight Against Multidrug-Resistant Bacteria 2005-2016: Modern Noninferiority Trial Designs Enable Antibiotic Development in Advance of Epidemic Bacterial Resistance.
Clin Infect Dis
; 65(1): 141-146, 2017 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29017263
15.
Efficient Delivery of Investigational Antibacterial Agents via Sustainable Clinical Trial Networks.
Clin Infect Dis
; 63 Suppl 2: S57-9, 2016 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27481955
16.
Confidence intervals for the difference between independent binomial proportions: comparison using a graphical approach and moving averages.
Pharm Stat
; 13(5): 294-308, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25163425
17.
Statistical considerations associated with a comprehensive regulatory framework to address the unmet need for new antibacterial therapies.
Pharm Stat
; 13(4): 222-8, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24931419
18.
Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study.
Infect Control Hosp Epidemiol
; 44(7): 1171-1173, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-36951472
19.
The Value of the Information That Can Be Generated: Optimizing Study Design to Enable the Study of Treatments Addressing an Unmet Need for Rare Pathogens.
Open Forum Infect Dis
; 9(7): ofac266, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35854983
20.
Active controlled studies in antibiotic drug development.
Pharm Stat
; 10(5): 454-60, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21956949